In addition to the clickable map, the games have the following changes from the RPGM versions:
No walking
No combat (the card game has been replaced with a simple win/lose choice)
No waiting for text or video to finish
Save anywhere

How to Play:
Normal RenPy commands apply: hold CTRL to skip text. The way the game is written, RenPy considers all text to be 'seen' after the first line in the game, so holding CTRL might skip a lot very fast.

On maps,
red/green squares are interactable objects (characters, items that can be picked up, exits...).
the blue square represents the location the Player Character is at. Probably.
you can use the mousewheel to zoom in, and click-drag to move the map around Google Maps style.
The game may chug a bit drawing each large map for the first time. Maps will be cached on disk after being rendered the first time.

Press 'q' to open the Quest Log (requires patch 0.8.1 or greater). Milf's Control is pretty inconsistent about how it uses the Quest Log, it will be blank for a while into the game and not everything is in it.